Letrozole Drug Description

Letrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer. It belongs to a class of drugs known Letrozol Labatec Filmtabletten 2.5mg 30 drug description as aromatase inhibitors, which work by lowering estrogen levels in the body. This reduction helps slow or stop the growth of certain types of breast tumors that require estrogen to grow.

Mechanism of Action

Letrozole functions by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogens in postmenopausal women. By blocking this conversion, letrozole effectively decreases circulating levels of estrogen, thereby depriving hormone-sensitive cancer cells of their growth signal.

Indications

The primary letrozole drug description includes its use for:

• Treatment of early-stage hormone receptor-positive breast cancer in postmenopausal women.
• Adjuvant therapy after surgery for breast cancer.
• Treatment of advanced breast cancer that has recurred or progressed following tamoxifen therapy.

Dosing Information

Letrozole is typically administered orally. The standard dose is:

1. 2.5 mg once daily.

Dosing may vary based on individual patient needs and response to treatment.

Side Effects

Common side effects associated with letrozole include:

• Hot flashes
• Joint pain
• Fatigue
• Nausea
• Bone thinning (osteoporosis)

Patients should report any severe or unusual symptoms to their healthcare provider promptly.

Precautions

Before starting letrozole, patients should inform their doctor about:

• Any allergies to medications.
• History of osteoporosis or bone fractures.
• Liver or kidney disease.
• Pregnancy or breastfeeding status.

FAQs

What should I do if I miss a dose of letrozole?

If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double up on doses.

Can letrozole be taken with other medications?

Always consult your healthcare provider before combining letrozole with other drugs, including over-the-counter medications and supplements, to avoid potential interactions.

How long will I need to take letrozole?

The duration of treatment varies depending on individual circumstances. Your oncologist will provide guidance based on your specific case.

In summary, letrozole is a critical component in the management of hormone receptor-positive breast cancer, particularly in postmenopausal women. Understanding its usage, side effects, and precautions can help patients make informed decisions regarding their treatment options.